Located approximately 10 minutes by car from Royal Palace of Naples, Mary & Ines Guest House Naples is merely 250 metres from Sant'Anna al Trivio. The guest house also includes a car park.

Stazione Napoli Centrale is not very far away, while Napoli Piazza Garibaldi train station is within close proximity of this Naples hotel. The area includes such religious sights as San Giovanni a Carbonara (1.1 km) and Gesu Nuovo Church (2.1 km). Piazza San Gaetano lies nearly a 20-minute stroll away, while Piazza Garibaldi is around a 10-minute walk from the accommodation. Ponte Casanova - Novara bus stop is a short way from Mary & Ines Guest House.

The Mary & Ines Guest House Naples offers rooms with a dining area complete with climate control. Bathrooms feature a separate toilet and a shower, along with comforts such as a hair dryer and bath sheets.

Guests can dine at the dessert restaurant Pasticceria Napolitano Poderico located approximately 5 minutes' walk away.